Lexington, SC Weather Forecast, with current conditions, wind, air quality, and what to expect for the next 3 days. Overcast 78°F 26°C More Information: Local Forecast Office More Local Wx 3 Day History Mobile Weather Hourly Weather Forecast Extended Forecast for Lexington SC Similar City Names Tonight Decreasing Clouds Low: 61 °F Sunday Sunny High: 85 °F Sunday Night Mostly Clear Low: 63 °F Monday Sunny High: 87 °F Monday Night Partly Cloudy Low: 65 °F Tuesday. Lexington, SC Hourly Weather | AccuWeather 7 PM 74° RealFeel® 71° 0% Partly sunny RealFeel Shade™ 71° Wind NE 9 mph Air Quality Fair Max UV Index 0 Low Wind Gusts 15 mph Humidity 46% Indoor.